Brand
name : Accomplia
has been found to stop both food and cigarette cravings enough
to help people quit smoking and lose weight, and could also help
curb other unhealthy urges.
The detailed information of use, precautions and
side effects is placed on our online pharmacy.
You may order on our online pharmacy WITHOUT A PRESCRIPTION.
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FULL DESCRIPTION
contains Rimonabant, the long awaited breakthrough drug
by Sanofi for the treatment of obesity and smoking cessation.
represents one of the latest and indeed a most novel
method for controlling body weight. operates by being
a cannabinoid receptor antagonist. This means that prevents
the normal action of endogenous cannabinoid in the brain from
stimulating the so-called CB1 receptors. It would appear that
these receptors stimulate appetite and therefore when they are “subdued” so
is the need to eat.
The clinical trials that have been run over the past few years
are impressive and have shown that these receptor sites may be
responsible for more than just appetite, because the results show
that also aids people to stop smoking and even improves
cardiovascular factors such as cholesterol ratios.
With specific regard to weight loss, the human trials have shown
an average weight loss of 10% of bodyweight, most importantly
that weight has remained off even up to 2-years later. Also importantly,
it would appear that the majority of weight is actually lost from
the difficult to lose area around the waist. The average figures
from the trials show a loss of fat of 20 lbs (9 Kg) and 3 inches
(8 cm) diameter taken off the waist.Additional trials have been
undertaken to help smokers kick the habit. Even here
has been successful, showing that persons
using have double the chance of quitting smoking for
good, and perhaps importantly also helping those smokers from
not gaining any weight once they stop smoking, (as it is often
the case that smokers trying to quit substitute their cigarettes
with food etc.).
On top of that, has also been shown to improve HDL (good
cholesterol) and triglyceride levels, showing benefit for diabetes
and heart conditions.Meanwhile, has shown few and minor
side effects in the clinical trials, some of which have been conducted
continuously
for 2-years. Side effects noted in the studies were mainly mild
and transient consisting (in order of frequency) of nausea, dizziness,
diarrhoea, vomiting, hypoglycaemia and anxiety.
The most beneficial doses noted in the trials have been 20 mg.
daily.
Active ingredients
The active substance is rimonabant. Each film-coated tablet of
contains 20mg of rimonabant. The other ingredients are:
Tablet Core: maize starch, lactose monohydrate, povidone K30 (E1201),
croscarmellose sodium (E468), sodium laurilsulfate (E487), miceocrystalline
cellulose (E 460), magnesium stearate.
Tablet coating: lactose monohydrate, hypromellose 15 mPa.s (E
464), titanium dioxide (E171), macrogol 3000.
Tablet polishing: carnauba wax (E 903)
The active ingredient of is rimonabant. It works by
blocking specific receptors in the brain and fat tissues called
CB1 receptors. is indicated in the treatment of obesity
and management of body weight as adjunct to diet and exercise.
Do not take :
* If you are (hypersensitive) allergic to rimonabant, or any
of the other ingredients of .
* If you are breast-feeding
TAKE SPECIAL CARE WITH
Tell your doctor before you take this medicine:
* If you have impaired liver
* If you have severely impaired renal function
* If you are currently being treated for epilepsy
* If you are less than 18 years of age. There is no information available on
the use of in people under 18 years of age.
TAKING OTHER MEDICINES:
The activity of is increased by simultaneous use of
some drugs (so-called CYP3A4 inhibitors) such as:
* itraconazole (antifungal medicine) * ketaconazole (antifungal
medicine) * ritonavir (medicine for the treatment of HIV infections)
* telithromycin (antibiotic)
* clarithromycin (antibiotic)
* nefazodone (anti-depressor)
Please tell your doctor or pharmacist if you are taking or have
recently taken the above mentioned medicines or any other medicines,
including those obtained without a prescription such as St. John’s
wort, rifampicin (antibiotic), medicines for weight loss, medicines
to improve blood lipids (fats), antidiabetes medicines and medicines
to treat epilepsy (e.g. phenytoin, Phenobarbital, carbamazeptine)
or depression
DRIVING AND USING MACHINES:
At the recommended dose, is not expected to reduce your
ability to drive and use machines.
PREGNANCY AND BREAST-FEEDING
should not be taken during pregnancy. Contact your doctor
immediately if you become pregnant, think you might be pregnant
or are planning to become pregnant while taking .
Do not take this medicine when breast-feeing. Tell your doctor
if you are breast-feeding or if you are planning to breast-feed
your baby.
IMPORTANT INFORMATION ABOUT SOME OF THE INGREDIENTS OF
tablets include lactose. If you are intolerant to some
sugars, contact your doctor before taking this medicine.
HOW TO TAKE
Always take exactly as your doctor has instructed you.
You should check with your doctor or pharmacist if you are unsure.
The usual dose is one 20mg tablet to be taken once daily in the
morning before breakfast. Swallow the tablet whole.
You need to start and continue a reduced calorie diet and a physical
activity program to get best results. Your doctor should recommend
the type of diet and the level of physical activity required,
that suits your specific condition and overall health.
Taking with food and drink
should be taken once daily in the morning before breakfast.
If you take more than you shouldTell your doctor or
pharmacist.
If you forget to take
Take it as soon as you remember but do not take a double dose
to make up for any forgotten dose.
POSSIBLE SIDE EFFECTS
Like all medicines, can cause side effects, although
not everybody gets them.
Very common side effects, that affect more than 1 per 10, have
occurred in patients on include:
* nausea and upper respiratory tract infection
Common side effects, that affect more than 1 per 100 but less
than 1 per 10, that have occurred in patients on include:
* upset stomach, vomiting, trouble with sleeping, depression,
irritability, dizziness, diarrhea, anxiety, itching, excessive
sweating, muscle cramps or spasm, fatigue, bruising, tendon pain
and inflammation (tendonitis), memory loss, back pain (sciatica),
altered sensitivity of the hands and feet, hot flush, fall, influenza,
and joint sprain.Uncommon side effects, that affects less than
1 per 100 but more than 1 per 1000, that have occurred in patients
on include:* sleepiness (lethargy), night sweats, panic
symptoms, hiccups, anger, restlessness (dysphoria), emotional
disorder.Rare side
effects, that affect less than 1 per 1000, that have occurred
in patients on include:* hallucinations
If any of the side effects gets serious, or if you notice any
side effects not listed in this leaflet, please tell your doctor
or pharmacist.
STORING
