Brand name: Accupril
Pronounced: AK-you-prill
Generic name: Quinapril hydrochloride
Why is prescribed?

is used in the treatment of high blood pressure. It can be taken alone or in combination with a thiazide type of water pill such as HydroDIURIL. is in a family of drugs known as "ACE inhibitors." It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form that increases salt and water retention in your body. also enhances blood flow throughout your blood vessels. Along with other drugs, is also prescribed in the treatment of congestive heart failure.
Most important fact about

You must take regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of ; and you must continue taking it even if you are feeling well. does not cure high blood pressure; it merely keeps it under control.
How should you take ?

You can take with or without meals.

Alcohol may increase the effect of , and could cause dizziness or fainting. Avoid alcoholic beverages until you have checked with your doctor.Take exactly as prescribed, and see your doctor regularly to make sure the drug is working properly without unwanted side effects. Do not stop taking without first consulting your doctor.

--If you miss a dose...

Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never try to "catch up" by doubling the dose.

--Storage instructions...

Accupril can be stored at room temperature. Protect from light.
side effects

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking .

* Side effects may include:
Dizziness, headache

Why should not be prescribed?

If you are sensitive to or have ever had an allergic reaction to or similar drugs, such as Capoten and Vasotec, you should not take . Make sure your doctor is aware of any drug reactions you have experienced.
Special warnings about

If you develop swelling of the face, lips, tongue, or throat, or of your arms and legs, or have difficulty swallowing or breathing, you should contact your doctor immediately. You may need emergency treatment.

If you develop abdominal pain with or without nausea and vomiting, contact your doctor. ACE inhibitors such as have been known to cause intestinal swelling.You may feel light-headed, especially during the first few days of therapy. If this occurs, notify your doctor. If you actually faint, stop taking until you have consulted with your doctor.Vomiting, diarrhea, and heavy perspiration can all deplete your body fluid; and dehydration can cause your blood pressure to drop. If this leads to light-headedness or fainting, you should check with your doctor.

Inform your doctor or dentist that you are taking before undergoing surgery or anesthesia.

Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor.

If you develop a sore throat, fever, or any other sign of infection, contact your doctor immediately. It could indicate a more serious illness.

If you are taking , your doctor will do a complete assessment of your kidney function and will watch it closely as long as you are taking .

If you notice a yellow tinge to your skin and the whites of your eyes, stop taking the drug and notify your doctor immediately. This could be a sign of liver damage.

The safety and effectiveness of in children have not been established.
Possible food and drug interactions when taking

If is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining with the following:

Diuretics such as Lasix
Lithium (Eskalith, Lithobid)
Magnesium
Potassium-sparing diuretics such as Aldactone, Dyazide, and Moduretic
Potassium supplements such as Slow-K and K-Dur
Salt substitutes containing potassium
Tetracycline (Sumycin)
Special information if you are pregnant or breastfeeding

ACE inhibitors such as have been shown to cause injury and even death to the unborn child when used in pregnancy during the second and third trimesters. If you are pregnant, your doctor should discontinue as soon as possible. If you plan to become pregnant, make sure your doctor knows you are taking . appears in breast milk and could affect a nursing infant. If is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.
Recommended dosage for

HIGH BLOOD PRESSURE

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

A severe drop in blood pressure is the primary sign of an overdose.