Brand
name: MEBEX (Mebendazole, Vermox)
GENERIC NAME: MEBENDAZOLE
(meh-BEN-duh-zole)
BRAND NAME(S): Vermox
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions
| Overdose | Notes | Missed Dose | Storage
Mebendazole belongs to the family of medicines called
anthelmintics. Anthelmintics are medicines used in the treatment of
worm infections.
Mebendazole is used to treat:
* Common roundworms (ascariasis);
* Hookworm infections (uncinariasis);
* Pinworms (enterobiasis; oxyuriasis);
* Whipworms (trichuriasis); and
* More than one worm infection at a time.
This medicine may also be used for other worm infections as determined
by your doctor.
Mebendazole works by keeping the worm from absorbing sugar (glucose).
This gradually causes loss of energy and death of the worm.
Mebendazole is available only with your doctor's prescription.
This product is available in the following dosage forms:
* Tablet, Chewable
* Suspension
Before Using MEBEX (Mebendazole, Vermox)
In deciding to use a medicine, the risks of taking the medicine must
be weighed against the good it will do. This is a decision you and
your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction
to this medicine or any other medicines. Also tell your health care
professional if you have any other types of allergies, such as to foods,
dyes, preservatives, or animals. For non-prescription products, read
the label or package ingredients carefully.
Pediatric
This medicine has been tested in a limited number of children 2 years
of age or older and, in effective doses, has not been shown to cause
different side effects or problems in children than it does in adults.
Geriatric
Many medicines have not been studied specifically in older people.
Therefore, it may not be known whether they work exactly the same way
they do in younger adults or if they cause different side effects or
problems in older people. There is no specific information comparing
use of mebendazole in the elderly with use in other age groups.
Pregnancy
Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are
no adequate studies in pregnant women OR no animal studies have been conducted
and there are no adequate studies in pregnant women.
Breastfeeding
There are no adequate studies in women for determining infant risk
when using this medication during breastfeeding. Weigh the potential
benefits against the potential risks before taking this medication
while breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in
other cases two different medicines may be used together even if an
interaction might occur. In these cases, your doctor may want to change
the dose, or other precautions may be necessary. Tell your healthcare
professional if you are taking any other prescription or nonprescription
(over-the-counter [OTC]) medicine.
Other Interactions
Certain medicines should not be used at or around the time of eating
food or eating certain types of food since interactions may occur.
Using alcohol or tobacco with certain medicines may also cause interactions
to occur. Discuss with your healthcare professional the use of your
medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this
medicine. Make sure you tell your doctor if you have any other medical
problems, especially:
* Crohn's disease or
* Liver disease or
* Ulcerative colitis—Patients with these diseases may have an increased
chance of side effects from mebendazole
Proper Use MEBEX (Mebendazole, Vermox)
Mebendazole usually comes with patient directions. Read them carefully
before using this medicine.
No special preparations or other steps (for example, special diets,
fasting, other medicines, laxatives, or enemas) are necessary before,
during, or immediately after taking mebendazole.
Mebendazole tablets may be chewed, swallowed whole, or crushed and
mixed with food.For patients taking mebendazole for hookworms, roundworms,
or whipworms:
* To help clear up your infection completely, take this medicine
exactly as directed by your doctor for the full time of treatment.
In some patients a second course of this medicine may be required to
clear up the infection completely. Do not miss any doses.
For patients taking mebendazole for pinworms:
* To help clear up your infection completely, take this medicine
exactly as directed by your doctor. A second course of this medicine
is usually required to clear up the infection completely.
* Pinworms may be easily passed from one person to another, especially in a
household. Therefore, all household members may have to be treated at the same
time. This helps to prevent infection or reinfection of other household members.
Also, all household members may have to be treated again in 2 to 3 weeks to
clear up the infection completely.
For patients taking mebendazole for infections in which high doses
are needed:
* Mebendazole is best taken with meals, especially fatty ones (for
example, meals that include whole milk or ice cream). This helps to
clear up the infection by helping your body absorb the medicine better.
However, if you are on a low-fat diet, check with your doctor.
Dosing MEBEX (Mebendazole, Vermox)
The dose of this medicine will be different for different patients.
Follow your doctor's orders or the directions on the label. The following
information includes only the average doses of this medicine. If your
dose is different, do not change it unless your doctor tells you to
do so.
The amount of medicine that you take depends on the strength of the
medicine. Also, the number of doses you take each day, the time allowed
between doses, and the length of time you take the medicine depend
on the medical problem for which you are using the medicine.
* For oral dosage form (chewable tablets):
o For common roundworms, hookworms, and whipworms:
+ Adults and children 2 years of age and over—100 milligrams (mg) two
times a day, morning and evening, for three days. Treatment may need to be
repeated in two to three weeks.
+ Children up to 2 years of age—Use and dose must be determined by your
doctor.
o For pinworms:
+ Adults and children 2 years of age and over—100 mg once a day for one
day. Treatment may need to be repeated in two to three weeks.
+ Children up to 2 years of age—Use and dose must be determined by your
doctor.
o For more than one worm infection at a time:
+ Adults and children 2 years of age and over—100 mg two times a day,
morning and evening, for three days.
+ Children up to 2 years of age—Use and dose must be determined by your
doctor.
Missed Dose
If you miss a dose of this medicine, take it as soon as possible.
However, if it is almost time for your next dose, skip the missed dose
and go back to your regular dosing schedule. Do not double doses.
Storage
Store the medicine in a closed container at room temperature, away
from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Precautions
It is important that your doctor check your progress at regular visits,
especially in infections in which high doses are needed. This is to
make sure that the infection is cleared up completely and to allow
your doctor to check for any unwanted effects.
If your symptoms do not improve within a few days, or if they become
worse, check with your doctor.
For patients taking mebendazole for pinworms:
* In some patients, pinworms may return after treatment with mebendazole.
Washing (not shaking) all bedding and nightclothes (pajamas) after
treatment may help to prevent this.
* Some doctors may also recommend other measures to help keep your infection
from returning. If you have any questions about this, check with your doctor.
For patients taking mebendazole for hookworms or whipworms :
* In hookworm and whipworm infections anemia may occur. Therefore,
your doctor may want you to take iron supplements to help clear up
the anemia. If so, it is important to take iron every day while you
are being treated for hookworms or whipworms; do not miss any doses.
Your doctor may also want you to keep taking iron supplements for up
to 6 months after you stop taking mebendazole. If you have any questions
about this, check with your doctor.
Side Effects MEBEX (Mebendazole, Vermox):
Along with its needed effects, a medicine may cause some unwanted
effects. Although not all of these side effects may occur, if they
do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following
side effects occur:
Rare
* Fever
* Skin rash or itching
* Sore throat and fever
* Unusual tiredness and weakness
Some side effects may occur that usually do not need medical attention.
These side effects may go away during treatment as your body adjusts
to the medicine. Also, your health care professional may be able to
tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side
effects continue or are bothersome or if you have any questions about
them:
Less common
* Abdominal or stomach pain or upset
* Diarrhea
* Nausea or vomiting , Dizziness
* Hair loss
* Headache
Other side effects not listed may also occur in some patients. If
you notice any other effects, check with your healthcare professional.
Mebendazole is used to treat intestinal worm infections such
as pinworm, round worm and hook worm.
HOW TO USE:
This medication is taken by mouth and can be taken with
or without food. It may be chewed or crushed, mixed and taken with
food. In Canada: The Canadian manufacturer states that their product
must not be chewed. For treatment of pinworm infections, the medication
is given as one single dose. If necessary, a second treatment may
be recommended in a few weeks.
SIDE EFFECTS:
This medication may cause stomach upset, loss of appetite,
diarrhea, fever, headache, dizziness, drowsiness or rash. If these
symptoms persist or become severe, inform your doctor. Very unlikely
but report promptly: dark urine, yellowing of the eyes or skin. In
the unlikely event you have an allergic reaction to this drug, seek
immediate medical attention. Symptoms of an allergic reaction include:
rash, itching, swelling, severe dizziness, trouble breathing. If
you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS:
Tell your doctor your medical history, especially of:
liver disease, malnutrition, anemia, any allergies you may have.
Mebendazole should be used only when clearly needed during pregnancy.
Discuss the
risks and benefits with your doctor. It is not known if mebendazole
is excreted into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS:
Tell your doctor of all medicines you may use (both
prescription and nonprescription), especially of: cimetidine, carbamazepine.
Do not start or stop any medicine without doctor or pharmacist approval.
