Brand name : Novorapid
( Novolog )
Brand names: Apidra, Humalog, Humulin, Iletin, Novolin,Novorapid,
Novolog
Why is Novorapid ( Insulin Glargine ) prescribed?
When is an insulin molecule a ‘foreign’ protein?
Pharmaceuticals will tell you the foreign
protein insulin source is the pancreas of a pig or cow. When given
names such as Humalog,
Lantus or NovoRapid by giant corporations, a foreign protein becomes
a wonderful ‘analog’ of human insulin. The truth is all three of these substances are foreign
proteins—in some cases
not even an insulin molecule. All could be considered new growth hormones
with very little being known about long term effects. Diabetics
need to apply for long-term guinea pig stat us.
Over the last 30 years, there have been over 2000
patents approved for various chemical compounds or processes used
to normalize blood sugar
metabolism. This
enormous interest is a 30-year ride on the money train called diabetes.
It’s also a good insight into the lack of progress in
the treatment of diabetes over the last 70-plus years. We
have replaced proven insulin protocols with less effective insulins.
Novorapid ( Insulin Glargine ) is prescribed for diabetes mellitus
when diet modifications and oral medications fail to correct the condition.
Novorapid ( Insulin Glargine ) is a hormone
produced by the pancreas, a large gland that lies near the stomach.
This hormone is necessary for the body's correct use of food, especially
sugar. Novorapid ( Insulin Glargine ) apparently works by helping
sugar penetrate the cell wall, where it is then utilized by the cell.
In people with diabetes,
the body either does not make enough Novorapid ( Insulin Glargine
), or the Novorapid ( Insulin Glargine ) that is produced cannot
be used properly.
There are actually two forms of diabetes: type 1 (Novorapid ( Insulin Glargine )-dependent)
and type 2 (non-Novorapid ( Insulin Glargine )-dependent). Type 1 usually requires Novorapid ( Insulin Glargine )
injection for life, while type 2 diabetes can usually be treated by
dietary changes and/or oral antidiabetic medications such as Diabinese,
Glucotrol, and Glucophage. Occasionally, type 2 diabetics must take
Novorapid ( Insulin Glargine ) injections on a temporary basis, especially during stressful
periods or times of illness.
The various available types of Novorapid ( Insulin Glargine ) differ in several ways: in
the source (animal, human, or genetically engineered), in the time
requirements for the Novorapid ( Insulin Glargine ) to take effect, and in the length of time
the Novorapid ( Insulin Glargine ) remains working.
Regular Novorapid ( Insulin Glargine ) is manufactured from beef and pork pancreas, begins
working within 30 to 60 minutes, and lasts for 6 to 8 hours. Variations
of Novorapid ( Insulin Glargine ) have been developed to satisfy the needs of individual patients.
For example, zinc suspension Novorapid ( Insulin Glargine ) is an intermediate-acting Novorapid ( Insulin Glargine )
that starts working within 1 to 1-1/2 hours and lasts approximately
24 hours. Novorapid ( Insulin Glargine ) combined with zinc and protamine is a longer-acting
Novorapid ( Insulin Glargine ) that takes effect within 4 to 6 hours and lasts up to 36 hours.
The time and course of action may vary considerably in different individuals
or at different times in the same individual. Genetically engineered
Novorapid ( Insulin Glargine ) works faster and for a shorter length of time than regular
human Novorapid ( Insulin Glargine ) and should be used along with a longer-acting Novorapid ( Insulin Glargine ).
It is available only by prescription.
Animal-based Novorapid ( Insulin Glargine ) is a very safe product. However, some components
may cause an allergic reaction (see "What side effects may occur?").
Therefore, genetically engineered human Novorapid ( Insulin Glargine ) has been developed
to lessen the chance of an allergic reaction. It is structurally identical
to the Novorapid ( Insulin Glargine ) produced by your body's pancreas. However, some human
Novorapid ( Insulin Glargine ) may be produced in a semi-synthetic process that begins with
animal-based ingredients, and may cause an allergic reaction.
Most important fact about Novorapid ( Insulin Glargine )
Regardless of the type of Novorapid ( Insulin Glargine ) your doctor has prescribed, you
should follow carefully the dietary and exercise guidelines he or she
has recommended. Failure to follow these guidelines or to take your
Novorapid ( Insulin Glargine ) as prescribed may result in serious and potentially life-threatening
complications such as hypoglycemia (lowered blood sugar levels).
How should you take Novorapid ( Insulin Glargine )?
Take your Novorapid ( Insulin Glargine ) exactly as prescribed, being careful to follow your
doctor's dietary and exercise recommendations. Before taking your injection,
carefully read and follow the manufacturer's instructions on how to
prepare your prefilled pen or syringe.
--If you miss a dose...
Your doctor should tell you what to do if you miss an Novorapid ( Insulin Glargine ) injection
or meal.
--Storage instructions...
Store Novorapid ( Insulin Glargine ) in a refrigerator (but not in the freezer) or in another
cool, dark place. Do not expose Novorapid ( Insulin Glargine ) to heat or direct sunlight.
Some brands of prefilled syringes can be kept at room temperature
for a week or a month. The vial or cartridge of genetically engineered
Novorapid ( Insulin Glargine ) lispro can be kept unrefrigerated for up to 28 days. Check
your product's label. Never use Novorapid ( Insulin Glargine ) after the expiration date which
is printed on the label and carton.
Novorapid ( Insulin Glargine ) side effects
While side effects from Novorapid ( Insulin Glargine ) use are rare, allergic reactions or
low blood sugar (sometimes called "an Novorapid ( Insulin Glargine ) reaction")
may pose significant health risks. Your doctor should be notified if
any of the following occur:
* Mild allergic reactions:
Swelling, itching or redness at the injection site (usually disappears within
a few days or weeks)
* More serious allergic reactions:
Fast pulse, low blood pressure, perspiration, rash over the entire body, shortness
of breath, shallow breathing, or wheezing
Other side effects are virtually eliminated when the correct dose
of Novorapid ( Insulin Glargine ) is matched with the proper diet and level of physical activity.
Low blood sugar may develop in poorly controlled or unstable diabetes.
Consuming sugar or a sugar-containing product will usually correct
the condition, which can be brought about by taking too much Novorapid ( Insulin Glargine ),
missing or delaying meals, exercising or working more than usual, an
infection or illness, a change in the body's need for Novorapid ( Insulin Glargine ), drug
interactions, or consuming alcohol.
* Symptoms of low blood sugar include:
Abnormal behavior, anxiety, blurred vision, cold sweat, confusion, depressed
mood, dizziness, drowsiness, fatigue, headache, hunger, inability to concentrate,
light-headedness, nausea, nervousness, personality changes, rapid heartbeat,
restlessness, sleep disturbances, slurred speech, sweating, tingling in the
hands, feet, lips, or tongue, tremor, unsteady movement
Contact your physician if these symptoms persist.
* Symptoms of more severe low blood sugar include:
Coma, disorientation
Remember, too, the symptoms associated with an under-supply of Novorapid ( Insulin Glargine ),
which can be brought on by taking too little of it, overeating, or
fever and infection.
* Symptoms of insufficient Novorapid ( Insulin Glargine ) include:
Drowsiness, flushing, fruity breath, heavy breathing, loss of appetite, rapid
pulse, thirst
If you are ill, you should check your urine for ketones (acetone),
and notify your doctor if the test is positive. This condition can
be life-threatening.
Why should Novorapid ( Insulin Glargine ) not be prescribed?
Novorapid ( Insulin Glargine ) should be used only to correct diabetic conditions.
Special warnings about Novorapid ( Insulin Glargine )
In the past few years a new rapid acting insulin has been marketed
by Lilly—Humalog. NovoRapid has been approved for sale by NovoNordisk in Europe. Lantus
has been approved
for sale as a basal insulin. The only natural basal insulin is beef
ultralente. Wear personal identification that states clearly that you
are diabetic. Carry a sugar-containing product such as hard candy to
offset any symptoms
of low blood sugar.
Do not change the type of Novorapid ( Insulin Glargine ) or even the model and brand of syringe
or needle you use without your physician's instruction. Failure to
use the proper syringe may lead to improper dosage levels of Novorapid ( Insulin Glargine ).
If you become ill from any cause, especially with nausea and vomiting
or fever, your Novorapid ( Insulin Glargine ) requirements may change. It is important to
eat as normally as possible. If you have trouble eating, drink fruit
juices, soda, or clear soups, or eat small amounts of bland foods.
Test your urine and/or blood sugar and tell your doctor at once. If
you have severe and prolonged vomiting, seek emergency medical care.
If you are taking Novorapid ( Insulin Glargine ), you should check your glucose levels with
home blood and urine testing devices. If your blood tests consistently
show above-normal sugar levels or your urine tests consistently show
the presence of sugar, your diabetes is not properly controlled, and
you should tell your doctor.
To avoid infection or contamination, use disposable needles and syringes
or sterilize your reusable syringe and needle carefully.
Always keep handy an extra supply of Novorapid ( Insulin Glargine ) as well as a spare syringe
and needle.
Possible food and drug interactions when taking Novorapid ( Insulin Glargine )
Follow your physician's dietary guidelines as closely as you can and
inform your physician of any medication, either prescription or non-prescription,
that you are taking. Specific medications, depending on the amount
present, that affect Novorapid ( Insulin Glargine ) levels or its effectiveness include:
ACE inhibitors such as the blood pressure medications Accupril and
Lotensin
Anabolic steroids such as Anadrol-50
Appetite suppressants such as Tenuate
Aspirin
Beta-blocking blood pressure medicines such as Tenormin and Lopressor
Diuretics such as Lasix and Dyazide
Epinephrine (EpiPen)
Estrogens such as Premarin
Isoniazid (Nydrazid)
Major tranquilizers such as Mellaril and Thorazine
MAO inhibitors (drugs such as the antidepressants Nardil and Parnate)
Niacin (Nicobid)
Octreotide (Sandostatin)
Oral contraceptives
Oral drugs for diabetes such as Diabinese and Orinase
Phenytoin (Dilantin)
Steroid medications such as prednisone
Sulfa antibiotics such as Bactrim and Septra
Thyroid medications such as Synthroid
Use alcohol carefully, since excessive alcohol consumption can cause
low blood sugar. Don't drink unless your doctor has approved it.
Special information if you are pregnant or breastfeeding
Novorapid ( Insulin Glargine ) is considered safe for pregnant women, but pregnancy may make
managing your diabetes more difficult.
Properly controlled diabetes is essential for the health of the mother
and the developing baby; therefore, it is extremely important that
pregnant women follow closely their physician's dietary and exercise
guidelines and prescribing instructions.
Since Novorapid ( Insulin Glargine ) does not pass into breast milk, it is safe for nursing
mothers. It is not known whether genetically engineered Novorapid ( Insulin Glargine ) lispro
appears in breast milk.
Recommended dosage for Novorapid ( Insulin Glargine )
Your doctor will specify which Novorapid ( Insulin Glargine ) to use, how much, when, and
how often to inject it. Your dosage may be affected by changes in food,
activity, illness, medication, pregnancy, exercise, travel, or your
work schedule. Proper control of your diabetes requires close and constant
cooperation with your doctor. Failure to use your Novorapid ( Insulin Glargine ) as prescribed
may result in serious and potentially fatal complications.
Some Novorapid ( Insulin Glargine )s should be clear, and some have a cloudy precipitate.
Find out what your Novorapid ( Insulin Glargine ) should look like and check it carefully
before using.
Genetically engineered Novorapid ( Insulin Glargine ) lispro injection should not be used
by children under age 12.
Overdosage
* An overdose of Novorapid ( Insulin Glargine ) can cause low blood sugar (hypoglycemia).
Symptoms include:
Depressed mood, dizziness, drowsiness, fatigue, headache, hunger, inability
to concentrate, irritability, nausea, nervousness, personality changes, rapid
heartbeat, restlessness, sleep disturbances, slurred speech, sweating, tingling,
tremor, unsteady movements
* Symptoms of more severe low blood sugar include:
Coma, disorientation, pale skin, seizures
