Brand name:
PRAVATOR (Pravastatin, Lipostat, Pravator)
Pronounced: PRAV-a-coll
Generic name: Pravastatin sodium
Why is Pravator prescribed?
Pravator is a cholesterol-lowering drug. Your doctor may prescribe
it along with a cholesterol-lowering diet if your blood cholesterol
level is dangerously high and you have not been able to lower it by
diet alone.
High cholesterol can lead to heart problems. By lowering your cholesterol,
Pravator improves your chances of avoiding a heart attack, heart surgery,
and death from heart disease. In people who already have hardening
of the arteries, it slows progression of the disease and cuts the risk
of acute attacks.
The drug works by helping to clear harmful low-density lipoprotein
(LDL) cholesterol out of the blood and by limiting the body's ability
to form new LDL cholesterol. For people at high risk of heart disease,
current guidelines call for considering drug therapy when LDL levels
reach 130. For people at lower risk, the cut-off is 160. For those
at little or no risk, it's 190.
Pravator can also be prescribed for children ages 8 and older when
diet alone fails to lower their cholesterol levels.
Most important fact about Pravator
Pravator is usually prescribed only if diet, exercise, and weight-loss
fail to bring your cholesterol levels under control. It's important
to remember that Pravator is a supplement--not a substitute--for those
other measures. To get the full benefit of the medication, you need
to stick to the diet and exercise program prescribed by your doctor.
All these efforts to keep your cholesterol levels normal are important
because together they may lower your risk of heart disease.
How should you take Pravator?
For an even greater cholesterol-lowering effect, your doctor may prescribe
Pravator along with a different kind of lipid-lowering drug such as
Questran or Colestid. However, you must not take Pravator at the same
time of day as the other cholesterol-lowering drug. Take Pravator
at least 1 hour before or 4 hours after taking the other drug.
Pravator should be taken once daily. You may take it anytime, with
or without food.
Your doctor will probably do blood tests for cholesterol levels every
4 weeks to determine the effectiveness of the dose.
If you miss a dose...
Take the forgotten dose as soon as you remember. If it is almost time
for your next dose, skip the one you missed and go back to your regular
schedule. Do not take a double dose.
Storage instructions PRAVATOR (Pravastatin, Lipostat, Pravachol)
Store at room temperature, in a tightly closed container, away from
moisture and light.
Pravator side effects
Side effects from Pravator cannot be anticipated. If any develop
or change in intensity, inform your doctor as soon as possible. Only
your doctor can determine if it is safe for you to continue taking
Pravator.
* Side effects may include:
Abdominal pain, chest pain, constipation, cough, diarrhea, dizziness, fatigue,
gas, headache, heartburn, inflammation of nasal passages, muscle aching or
weakness, nausea, rash, stomach or intestinal discomfort, urinary problems,
vomiting
Why should Pravator not be prescribed?
Do not take Pravator if you are sensitive or have ever had an allergic
reaction to it.
Do not take Pravator if you have liver disease.
Special warnings about Pravator
Pravator should not be used to try to lower high cholesterol that
stems from a medical condition such as alcoholism, poorly controlled
diabetes, an underactive thyroid gland, or a kidney or liver problem.
Because Pravator may cause damage to the liver, your doctor will
probably do blood tests before you start taking the drug and whenever
he plans a dosage increase. The doctor should monitor you especially
carefully if you've recently had liver disease, if you have any symptoms
that might mean liver disease, or if you're a heavy drinker.
Since Pravator may cause damage to muscle tissue, promptly report
to your doctor any unexplained muscle pain, tenderness, or weakness,
especially if you also have a fever or you just generally do not feel
well.
Possible food and drug interactions when taking Pravator
If Pravator is taken with certain other drugs, the effects of either
could be increased, decreased, or altered. It is especially important
to check with your doctor before combining Pravator with the following:
Cholestyramine (Questran)
Cimetidine (Tagamet)
Colestipol (Colestid)
Diltiazem (Cardizem, Dilacor, Tiazac)
Drugs that suppress the immune system, such as Sandimmune and Neoral
Erythromycin (E.E.S., Erythrocin, others)
Gemfibrozil (Lopid)
Itraconazole (Sporanox)
Niacin (Niacor, Niaspan)
Warfarin (Coumadin)
Special information if you are pregnant or breastfeeding
You must not become pregnant while taking Pravator. Because this
drug lowers cholesterol, and cholesterol is necessary for the proper
development of an unborn baby, there is some suspicion that Pravator
might cause birth defects. Your doctor will prescribe Pravator only
if you are highly unlikely to become pregnant while taking the drug.
If you do become pregnant while taking Pravator, inform your doctor
immediately.
Because Pravator appears in breast milk, and because its cholesterol-lowering
effects might prove harmful to a nursing baby, you should not take
Pravator while you are breastfeeding.
Recommended dosage for PRAVATOR (Pravastatin, Lipostat,
Pravachol)
ADULTS
Overdosage
