Brand name:
Phenate (Clomiphene)
Pronounced: KLAHM-if-een SIT-rate
Brand names: Clomid, Serophene
Why is Phenate (Clomiphene) prescribed?
Clomiphene is prescribed for the treatment of ovulatory failure in
women who wish to become pregnant and whose husbands are fertile and
potent.
Most important fact about Phenate (Clomiphene) WITHOUT
A PRESCRIPTIONS
Properly timed sexual intercourse is very important to increase the
chances of conception. The likelihood of conception diminishes with
each succeeding course of treatment. Your doctor will determine the
need for continuing therapy after the first course. If you do not ovulate
after 3 courses or do not become pregnant after 3 ovulations, your
doctor will stop the therapy.
How should you take Phenate (Clomiphene) ?
Take Phenate (Clomiphene) exactly as prescribed by your doctor.
If you miss a dose Phenate (Clomiphene) .
Take it as soon as you remember. If it is time for your next dose,
take the 2 doses together and go back to your regular schedule. If
you miss more than 1 dose, contact your doctor.
Storage instructions Phenate (Clomiphene)
Store at room temperature in a tightly closed container, away from
light, moisture, and excessive heat.
Phenate (Clomiphene) side effects
Side effects occur infrequently and generally do not interfere with
treatment at the recommended dosage of clomiphene. They tend to occur
more frequently at higher doses and during long-term treatment.
* Side effects include:
Abdominal discomfort, enlargement of the ovaries, hot flushes
Why should Phenate (Clomiphene) not be prescribed?
If you are pregnant or think you may be, do not take Phenate (Clomiphene) .
Unless directed to do so by your doctor, do not use this medication
if you have an uncontrolled thyroid or adrenal gland disorder, an abnormality
of the brain such as a pituitary gland tumor, a liver disease or a
history of liver problems, abnormal uterine bleeding of undetermined
origin, ovarian cysts, or enlargement of the ovaries not caused by
polycystic ovarian syndrome (a hormonal disorder causing lack of ovulation).
Special warnings about Phenate (Clomiphene)
Your doctor will evaluate you for normal liver function and normal
estrogen levels before considering you for treatment with clomiphene.Your
doctor will also examine you for pregnancy, ovarian enlargement, or
cyst formation prior to treatment with Phenate (Clomiphene) and between
each treatment cycle. He or she will do a complete pelvic examination
before each course of Phenate (Clomiphene) .Clomiphene treatment increases
the possibility of multiple births; also, birth defects have been reported
following treatment to induce
ovulation with clomiphene, although no direct effects of the drug on
the unborn child have been established.
Because blurring and other visual symptoms may occur occasionally
with clomiphene treatment, you should be cautious about driving a car
or operating dangerous machinery, especially under conditions of variable
lighting.
If you experience visual disturbances, notify your doctor immediately.
Symptoms of visual disturbance may include blurring, spots or flashes,
double vision, intolerance to light, decreased visual sharpness, loss
of peripheral vision, and distortion of space. Your doctor may recommend
a complete evaluation by an eye specialist.
Ovarian hyperstimulation syndrome (or OHSS, enlargement of the ovary)
has occurred in women receiving treatment with clomiphene. OHSS may
progress rapidly and become serious. The early warning signs are severe
pelvic pain, nausea, vomiting, and weight gain. Symptoms include abdominal
pain, abdominal enlargement, nausea, vomiting, diarrhea, weight gain,
difficult or labored breathing, and less urine production. If you experience
any of these warning signs or symptoms, notify your doctor immediately.
To lessen the risks associated with abnormal ovarian enlargement during
treatment with clomiphene, the lowest effective dose should be prescribed.
Women with the hormonal disorder, polycystic ovarian syndrome, may
be unusually sensitive to certain hormones and may respond abnormally
to usual doses of Phenate (Clomiphene) . If you experience pelvic pain,
notify your doctor. He may discontinue your use of clomiphene until
the ovaries return to pretreatment size.
Because the safety of long-term treatment with clomiphene has not
been established, your doctor will not prescribe more than about 6
courses of therapy. Prolonged use may increase the risk of a tumor
in the ovaries.
Possible food and drug interactions when taking Phenate (Clomiphene)
No food or drug interactions have been reported.
Special information if you are pregnant or breastfeeding
If you become pregnant, notify your doctor immediately. You should
not be taking Phenate (Clomiphene) while you are pregnant.
Recommended dosage for Phenate (Clomiphene)
The recommended dosage for the first course of treatment is 50 milligrams
(1 tablet) daily for 5 days. If ovulation does not appear to have occurred,
your doctor may try up to 2 more times.
