Brand name:Avandia
Pronounced: AH-van-DEE-ah
Generic name: Rosiglitazone maleate
Why is Avandia prescribed?
Avandia is used to hold down blood sugar levels in people with type
2 diabetes (also known as "non-insulin dependent" or "adult
onset" diabetes).
Blood sugar levels are ordinarily controlled by the body's natural
supply of insulin, which helps sugar move out of the bloodstream and
into the cells. In type 2 diabetes, the buildup of sugar in the blood
is often due not to a lack of insulin, but to the body's inability
to make proper use of it. Avandia works first by decreasing sugar production,
then by helping the body make more efficient use of whatever insulin
is available. It does not increase the actual amount of insulin in
circulation.
Avandia is a new type of diabetes medication. It can be used alone
or in conjunction with insulin, metformin (Glucophage), or a member
of the sulfonylurea class of diabetes drugs (Diabinese, Micronase,
Orinase). It takes effect slowly. You may not see a reduction in blood
sugar levels for the first 2 weeks of therapy, and it may take 2 to
3 months for Avandia to deliver maximum results.
Most important fact about Avandia
Always remember that Avandia is an aid to, not a substitute for, good
diet, weight loss, and exercise. Failure to follow a sound diet and
exercise plan can lead to serious complications, such as dangerously
high or low blood sugar levels. Remember, too, that Avandia is not
an oral form of insulin, and cannot be used in place of insulin.
How should you take Avandia?
Your dose of Avandia may be taken once a day in the morning or divided
in half and taken in the morning and evening, with or without food.
If you miss a dose...
Take it as soon as you remember. If it is almost time for the next
dose, skip the one you missed and go back to your regular schedule.
Do not take 2 doses at once.
Storage instructions Avandia (Rosiglitazone)
Store at room temperature in a tight, light-resistant container.
Avandia side effects
Side effects cannot be anticipated. If any develop or change in intensity,
inform your doctor as soon as possible. Only your doctor can determine
if it is safe for you to continue taking Avandia.
* Side effects may include:
Back pain, fatigue, headache, high blood sugar, low blood sugar, respiratory
tract infections, sinus inflammation, swelling
Why should Avandia not be prescribed?
Do not take Avandia if it has ever given you an allergic reaction.
Special warnings about Avandia
If you have liver disease, you should not take Avandia. Your doctor
will check to make sure your liver function is normal before prescribing
Avandia, then recheck it every 2 months for the first 12 months and
periodically thereafter. Warning signs of liver damage include nausea,
vomiting, abdominal pain, fatigue, loss of appetite, and dark urine.
If you develop any of these symptoms, tell your doctor immediately.
You may need to discontinue treatment with Avandia.
People taking Avandia in combination with insulin or other diabetes
drugs sometimes develop low blood sugar. If this happens, check with
your doctor. The dosage of the other diabetes drug may have to be reduced.
People with kidney problems can take Avandia, but should not take
Glucophage. If you have poor kidney function, you'll be unable to take
advantage of this combination.
Avandia can increase the chances of conception. Be sure to use some
form of birth control if you don't want a pregnancy.
Avandia won't help type 1 diabetics, who are unable to produce any
insulin at all. Insulin shots are a necessity for this form of the
illness. Nor can Avandia relieve diabetic ketoacidosis (excessively
high sugar levels due to lack of insulin).
Use Avandia with caution if you have a problem with fluid retention
or swelling. The drug has been known to cause this problem, which in
turn can lead to heart failure or other heart problems. Avandia should
be avoided by anyone who has been diagnosed with heart failure, and
it should be discontinued by anyone who develops it. Make sure the
doctor is aware of any heart problems you may have. Alert him immediately
if you develop symptoms of heart failure such as fatigue and shortness
of breath.
If you are being treated with Avandia and insulin you will need to
be monitored for heart problems. Notify your doctor if you develop
any unusual swelling or a rapid weight increase.
You should be aware that people taking Avandia tend to gain a little
weight, typically around 5 to 10 pounds. The cause is thought to be
a combination of fluid retention and fat accumulation.
Avandia is not recommended for children under 18.
Possible food and drug interactions when taking Avandia
No drug interactions with Avandia have been reported at this time.
Special information if you are pregnant or breastfeeding
It's important to maintain normal blood sugar levels while pregnant,
but the safety of Avandia during pregnancy remains unproven. Since
insulin shots are known to be safe, your doctor may switch you from
Avandia to insulin until the baby is born.
It is not known whether Avandia appears in breast milk. Because many
drugs do find their way into breast milk, however, the safest bet is
to avoid taking Avandia while nursing.
Recommended dosage for Avandia
ADULTS
Overdosage
