Brand name : Lantus
Optipen ( Lantus Optipen ( Insulin Glargine ) Glargine )
Pronounced: IN-suh-lin
Brand names: Apidra, Humalog, Humulin, Iletin, Novolin
Why is Lantus Optipen ( Insulin Glargine ) prescribed?
Lantus Optipen ( Insulin Glargine ) is prescribed for diabetes mellitus when diet modifications
and oral medications fail to correct the condition. Lantus Optipen ( Insulin Glargine ) is a hormone
produced by the pancreas, a large gland that lies near the stomach.
This hormone is necessary for the body's correct use of food, especially
sugar. Lantus Optipen ( Insulin Glargine ) apparently works by helping sugar penetrate the cell
wall, where it is then utilized by the cell. In people with diabetes,
the body either does not make enough Lantus Optipen ( Insulin Glargine ), or the Lantus Optipen ( Insulin Glargine ) that is
produced cannot be used properly.
There are actually two forms of diabetes: type 1 (Lantus Optipen ( Insulin Glargine )-dependent)
and type 2 (non-Lantus Optipen ( Insulin Glargine )-dependent). Type 1 usually requires Lantus Optipen ( Insulin Glargine )
injection for life, while type 2 diabetes can usually be treated by
dietary changes and/or oral antidiabetic medications such as Diabinese,
Glucotrol, and Glucophage. Occasionally, type 2 diabetics must take
Lantus Optipen ( Insulin Glargine ) injections on a temporary basis, especially during stressful
periods or times of illness.
The various available types of Lantus Optipen ( Insulin Glargine ) differ in several ways: in
the source (animal, human, or genetically engineered), in the time
requirements for the Lantus Optipen ( Insulin Glargine ) to take effect, and in the length of time
the Lantus Optipen ( Insulin Glargine ) remains working.
Regular Lantus Optipen ( Insulin Glargine ) is manufactured from beef and pork pancreas, begins
working within 30 to 60 minutes, and lasts for 6 to 8 hours. Variations
of Lantus Optipen ( Insulin Glargine ) have been developed to satisfy the needs of individual patients.
For example, zinc suspension Lantus Optipen ( Insulin Glargine ) is an intermediate-acting Lantus Optipen ( Insulin Glargine )
that starts working within 1 to 1-1/2 hours and lasts approximately
24 hours. Lantus Optipen ( Insulin Glargine ) combined with zinc and protamine is a longer-acting
Lantus Optipen ( Insulin Glargine ) that takes effect within 4 to 6 hours and lasts up to 36 hours.
The time and course of action may vary considerably in different individuals
or at different times in the same individual. Genetically engineered
Lantus Optipen ( Insulin Glargine ) works faster and for a shorter length of time than regular
human Lantus Optipen ( Insulin Glargine ) and should be used along with a longer-acting Lantus Optipen ( Insulin Glargine ).
It is available only by prescription.
Animal-based Lantus Optipen ( Insulin Glargine ) is a very safe product. However, some components
may cause an allergic reaction (see "What side effects may occur?").
Therefore, genetically engineered human Lantus Optipen ( Insulin Glargine ) has been developed
to lessen the chance of an allergic reaction. It is structurally identical
to the Lantus Optipen ( Insulin Glargine ) produced by your body's pancreas. However, some human
Lantus Optipen ( Insulin Glargine ) may be produced in a semi-synthetic process that begins with
animal-based ingredients, and may cause an allergic reaction.
Most important fact about Lantus Optipen ( Insulin Glargine )
Regardless of the type of Lantus Optipen ( Insulin Glargine ) your doctor has prescribed, you
should follow carefully the dietary and exercise guidelines he or she
has recommended. Failure to follow these guidelines or to take your
Lantus Optipen ( Insulin Glargine ) as prescribed may result in serious and potentially life-threatening
complications such as hypoglycemia (lowered blood sugar levels).
How should you take Lantus Optipen ( Insulin Glargine )?
Take your Lantus Optipen ( Insulin Glargine ) exactly as prescribed, being careful to follow your
doctor's dietary and exercise recommendations. Before taking your injection,
carefully read and follow the manufacturer's instructions on how to
prepare your prefilled pen or syringe.
--If you miss a dose...
Your doctor should tell you what to do if you miss an Lantus Optipen ( Insulin Glargine ) injection
or meal.
--Storage instructions...
Store Lantus Optipen ( Insulin Glargine ) in a refrigerator (but not in the freezer) or in another
cool, dark place. Do not expose Lantus Optipen ( Insulin Glargine ) to heat or direct sunlight.
Some brands of prefilled syringes can be kept at room temperature
for a week or a month. The vial or cartridge of genetically engineered
Lantus Optipen ( Insulin Glargine ) lispro can be kept unrefrigerated for up to 28 days. Check
your product's label. Never use Lantus Optipen ( Insulin Glargine ) after the expiration date which
is printed on the label and carton.
Lantus Optipen ( Insulin Glargine ) side effects
While side effects from Lantus Optipen ( Insulin Glargine ) use are rare, allergic reactions or
low blood sugar (sometimes called "an Lantus Optipen ( Insulin Glargine ) reaction")
may pose significant health risks. Your doctor should be notified if
any of the following occur:
* Mild allergic reactions:
Swelling, itching or redness at the injection site (usually disappears within
a few days or weeks)
* More serious allergic reactions:
Fast pulse, low blood pressure, perspiration, rash over the entire body, shortness
of breath, shallow breathing, or wheezing
Other side effects are virtually eliminated when the correct dose
of Lantus Optipen ( Insulin Glargine ) is matched with the proper diet and level of physical activity.
Low blood sugar may develop in poorly controlled or unstable diabetes.
Consuming sugar or a sugar-containing product will usually correct
the condition, which can be brought about by taking too much Lantus Optipen ( Insulin Glargine ),
missing or delaying meals, exercising or working more than usual, an
infection or illness, a change in the body's need for Lantus Optipen ( Insulin Glargine ), drug
interactions, or consuming alcohol.
* Symptoms of low blood sugar include:
Abnormal behavior, anxiety, blurred vision, cold sweat, confusion, depressed
mood, dizziness, drowsiness, fatigue, headache, hunger, inability to concentrate,
light-headedness, nausea, nervousness, personality changes, rapid heartbeat,
restlessness, sleep disturbances, slurred speech, sweating, tingling in the
hands, feet, lips, or tongue, tremor, unsteady movement
Contact your physician if these symptoms persist.
* Symptoms of more severe low blood sugar include:
Coma, disorientation
Remember, too, the symptoms associated with an under-supply of Lantus Optipen ( Insulin Glargine ),
which can be brought on by taking too little of it, overeating, or
fever and infection.
* Symptoms of insufficient Lantus Optipen ( Insulin Glargine ) include:
Drowsiness, flushing, fruity breath, heavy breathing, loss of appetite, rapid
pulse, thirst
If you are ill, you should check your urine for ketones (acetone),
and notify your doctor if the test is positive. This condition can
be life-threatening.
Why should Lantus Optipen ( Insulin Glargine ) not be prescribed?
Lantus Optipen ( Insulin Glargine ) should be used only to correct diabetic conditions.
Special warnings about Lantus Optipen ( Insulin Glargine )
Wear personal identification that states clearly that you are diabetic.
Carry a sugar-containing product such as hard candy to offset any symptoms
of low blood sugar.
Do not change the type of Lantus Optipen ( Insulin Glargine ) or even the model and brand of syringe
or needle you use without your physician's instruction. Failure to
use the proper syringe may lead to improper dosage levels of Lantus Optipen ( Insulin Glargine ).
If you become ill from any cause, especially with nausea and vomiting
or fever, your Lantus Optipen ( Insulin Glargine ) requirements may change. It is important to
eat as normally as possible. If you have trouble eating, drink fruit
juices, soda, or clear soups, or eat small amounts of bland foods.
Test your urine and/or blood sugar and tell your doctor at once. If
you have severe and prolonged vomiting, seek emergency medical care.
If you are taking Lantus Optipen ( Insulin Glargine ), you should check your glucose levels with
home blood and urine testing devices. If your blood tests consistently
show above-normal sugar levels or your urine tests consistently show
the presence of sugar, your diabetes is not properly controlled, and
you should tell your doctor.
To avoid infection or contamination, use disposable needles and syringes
or sterilize your reusable syringe and needle carefully.
Always keep handy an extra supply of Lantus Optipen ( Insulin Glargine ) as well as a spare syringe
and needle.
Possible food and drug interactions when taking Lantus Optipen ( Insulin Glargine )
Follow your physician's dietary guidelines as closely as you can and
inform your physician of any medication, either prescription or non-prescription,
that you are taking. Specific medications, depending on the amount
present, that affect Lantus Optipen ( Insulin Glargine ) levels or its effectiveness include:
ACE inhibitors such as the blood pressure medications Accupril and
Lotensin
Anabolic steroids such as Anadrol-50
Appetite suppressants such as Tenuate
Aspirin
Beta-blocking blood pressure medicines such as Tenormin and Lopressor
Diuretics such as Lasix and Dyazide
Epinephrine (EpiPen)
Estrogens such as Premarin
Isoniazid (Nydrazid)
Major tranquilizers such as Mellaril and Thorazine
MAO inhibitors (drugs such as the antidepressants Nardil and Parnate)
Niacin (Nicobid)
Octreotide (Sandostatin)
Oral contraceptives
Oral drugs for diabetes such as Diabinese and Orinase
Phenytoin (Dilantin)
Steroid medications such as prednisone
Sulfa antibiotics such as Bactrim and Septra
Thyroid medications such as Synthroid
Use alcohol carefully, since excessive alcohol consumption can cause
low blood sugar. Don't drink unless your doctor has approved it.
Special information if you are pregnant or breastfeeding
Lantus Optipen ( Insulin Glargine ) is considered safe for pregnant women, but pregnancy may make
managing your diabetes more difficult.
Properly controlled diabetes is essential for the health of the mother
and the developing baby; therefore, it is extremely important that
pregnant women follow closely their physician's dietary and exercise
guidelines and prescribing instructions.
Since Lantus Optipen ( Insulin Glargine ) does not pass into breast milk, it is safe for nursing
mothers. It is not known whether genetically engineered Lantus Optipen ( Insulin Glargine ) lispro
appears in breast milk.
Recommended dosage for Lantus Optipen ( Insulin Glargine )
Your doctor will specify which Lantus Optipen ( Insulin Glargine ) to use, how much, when, and
how often to inject it. Your dosage may be affected by changes in food,
activity, illness, medication, pregnancy, exercise, travel, or your
work schedule. Proper control of your diabetes requires close and constant
cooperation with your doctor. Failure to use your Lantus Optipen ( Insulin Glargine ) as prescribed
may result in serious and potentially fatal complications.
Some Lantus Optipen ( Insulin Glargine )s should be clear, and some have a cloudy precipitate.
Find out what your Lantus Optipen ( Insulin Glargine ) should look like and check it carefully
before using.
Genetically engineered Lantus Optipen ( Insulin Glargine ) lispro injection should not be used
by children under age 12.
Overdosage
* An overdose of Lantus Optipen ( Insulin Glargine ) can cause low blood sugar (hypoglycemia).
Symptoms include:
Depressed mood, dizziness, drowsiness, fatigue, headache, hunger, inability
to concentrate, irritability, nausea, nervousness, personality changes, rapid
heartbeat, restlessness, sleep disturbances, slurred speech, sweating, tingling,
tremor, unsteady movements
* Symptoms of more severe low blood sugar include:
Coma, disorientation, pale skin, seizures
