Brand
name:
OVRAL-L (Ovranette, Levlen, Levora, Nordette)
Brand names: Alesse, Apri, Brevicon, Cyclessa, Demulen, Desogen, Estrostep,
Levlen, Levlite, Levora, Loestrin, Lo/Ovral, Low-Ogestrel, Micronor,
Mircette, Modicon, Necon, Nordette, Norinyl, Nor-QD, Ogestrel, Ortho-Cept,
Ortho-Cyclen, Ortho-Novum, Ortho Tri-Cyclen, Ovcon, Ovral, Ovrette, Tri-Levlen,
Tri-Norinyl, Triphasil, Trivora, Yasmin, Zovia
Why are OVRAL-L (Ovranette, Levlen, Levora, Nordette) prescribed?
OVRAL-L (Ovranette, Levlen, Levora, Nordette) (also known as "the pill") are highly
effective means of preventing pregnancy. OVRAL-L (Ovranette, Levlen, Levora, Nordette) consist
of synthetic forms of two hormones produced naturally in the body:
either progestin alone or estrogen and progestin. Estrogen and progestin
regulate a woman's menstrual cycle, and the fluctuating levels of these
hormones play an essential role in fertility.
To reduce side effects, OVRAL-L (Ovranette, Levlen, Levora, Nordette) are available in a wide
range of estrogen and progestin concentrations. Progestin-only products
(such as Micronor) are usually prescribed for women who should avoid
estrogens; however, they may not be as effective as estrogen/progestin
contraceptives.
One variety of the Pill--the Ortho Tri-Cyclen 28-day Dialpak--is also
used in the treatment of moderate acne in women aged 15 and older.
It is taken just as it would be for contraception.
Most important fact about OVRAL-L (Ovranette, Levlen, Levora, Nordette)
Cigarette smoking increases the risk of serious heart-related side
effects (stroke, heart attack, blood clots, etc.) in women who use
OVRAL-L (Ovranette, Levlen, Levora, Nordette). This risk increases with heavy smoking (15 or
more cigarettes per day) and with age. There is an especially significant
increase in heart disease risk in women over 35 years old who smoke
and use OVRAL-L (Ovranette, Levlen, Levora, Nordette).
How should you take OVRAL-L (Ovranette, Levlen, Levora, Nordette)?
OVRAL-L (Ovranette, Levlen, Levora, Nordette) should be taken daily, no more than 24 hours apart,
for the duration of the prescribed cycle of 21 or 28 days. Start the
cycle according to package directions. Ideally, you should take your
pill at the same time every day to reduce the chance of forgetting
a dose; with progestin-only contraceptives, taking the pill at the
same time each day is essential.
If you miss a dose...
If you neglect to take only one estrogen/progestin pill, take it as
soon as you remember, take the next pill at your regular time, and
continue taking the rest of OVRAL-L (Ovranette, Levlen, Levora, Nordette) cycle. The risk of
pregnancy is small if you miss only one combination pill per cycle.
If you miss more than one tablet, check your product's patient information
for instructions.
Missing a single progestin-only tablet increases the chance of pregnancy.
Consult your doctor immediately if you miss a single dose or if you
take it 3 or more hours late, and use another method of birth control
until your next period begins or pregnancy is ruled out.
Storage instructions...
To help keep track of your doses, use the original container. Store
at room temperature.
OVRAL-L (Ovranette, Levlen, Levora, Nordette) side effects
Side effects cannot be anticipated. If any develop or change in intensity,
inform your doctor as soon as possible. Only your doctor can determine
if it is safe for you to continue taking an oral contraceptive.
* Side effects may include:
Breakthrough bleeding between menstrual periods (spotting), depression, loss
of menstrual periods, migraine, nausea, vomiting, water retention, weight
gain, yeast infection
Why should OVRAL-L (Ovranette, Levlen, Levora, Nordette) not be prescribed?
You should not take OVRAL-L (Ovranette, Levlen, Levora, Nordette) if you have had an allergic
reaction to them or if you are pregnant (or think you might be). Avoid
them, too, if you suffer from migraine headaches preceded by an aura
(visual disturbances such as pulsing lights and blind spots, temporary
numbness, and similar symptoms).
If you have ever had breast cancer or cancer in the reproductive organs
or liver tumors, you should not take OVRAL-L (Ovranette, Levlen, Levora, Nordette).
If you have or have ever had a stroke, heart disease, liver disease,
angina (severe chest pain), or blood clots, you should not take OVRAL-L (Ovranette, Levlen, Levora, Nordette). They are not recommended for women with significant
high blood pressure. Women who have had pregnancy-related jaundice
or jaundice stemming from previous use of OVRAL-L (Ovranette, Levlen, Levora, Nordette) should
not take them.
If you have undiagnosed and/or unexplained abnormal vaginal bleeding,
do not take OVRAL-L (Ovranette, Levlen, Levora, Nordette).
In addition, if you have liver, kidney, or adrenal disease, you should
avoid the Yasmin brand of oral contraceptive. It contains an ingredient
that can increase potassium levels in the body, leading to serious
problems if you have one of these diseases.
Finally, you should not take OVRAL-L (Ovranette, Levlen, Levora, Nordette) if you are having
major surgery with a prolonged period of being immobile.
Special warnings about OVRAL-L (Ovranette, Levlen, Levora, Nordette)
OVRAL-L (Ovranette, Levlen, Levora, Nordette) should be used with caution if you are over 40
years old; smoke tobacco; have liver, heart, gallbladder, kidney, or
thyroid disease; have high blood pressure, high cholesterol, diabetes,
epilepsy, asthma, or porphyria (a blood disorder); or tend to be seriously
overweight. Caution is also advised if you have blood circulation problems
or have had a heart attack or stroke in the past. Be cautious, too,
if you have problems with depression, migraine or other headaches,
irregular menstrual periods, or visual disturbances.
Because OVRAL-L (Ovranette, Levlen, Levora, Nordette) may speed up development of gallbladder
disease, see your doctor right away if you develop symptoms such as
sharp stomach pains, fever, or nausea and vomiting.
If you have a family history of breast cancer or other cancers, you
might want to consider using a progestin-only product. The estrogen
in combination OVRAL-L (Ovranette, Levlen, Levora, Nordette) has been linked with an increase
in the risk of breast cancer during use of the pill, though this added
risk appears to decrease once you stop taking it. If you do use a combination,
choose one with a relatively low amount of estrogen. Take high-estrogen
pills (0.05 milligrams of estrogen) only if your doctor feels it's
necessary.
You should also be aware that some studies link OVRAL-L (Ovranette, Levlen, Levora, Nordette)
with an increased risk of cervical cancer. However, some experts think
other factors besides the pill are to blame.
Since the blood's clotting ability may be affected by OVRAL-L (Ovranette, Levlen, Levora, Nordette),
your doctor may take you off them prior to surgery. If bleeding lasts
more than 8 days while you are on a progestin-only oral contraceptive,
or if you have no period at all, be sure to let your doctor know. The
risk of blood clots is greater with OVRAL-L (Ovranette, Levlen, Levora, Nordette) that contain
desogestrel, such as Ortho-Cept. This risk is also higher during the
first year you take a combined oral contraceptive.
OVRAL-L (Ovranette, Levlen, Levora, Nordette) do not protect against HIV infection (AIDS) or
any other sexually transmitted disease. If there is a danger of infection,
use a latex condom and spermicide in addition to the pill.
If you develop a migraine or severe headache that does not let up
or keeps recurring while you are taking a progestin-only oral contraceptive,
check with your doctor. You may need to switch to a different type
of pill.
If you miss a menstrual period but have taken your pills regularly,
contact your doctor but do not stop taking your pills. If you miss
a period and have not taken your pills regularly, or if you miss two
consecutive periods, you may be pregnant; stop taking your pills and
check with your doctor immediately to see if you are pregnant. Use
another form of birth control while you are not taking your pills.
If you are taking a progestin-only oral contraceptive and you have
sudden or severe abdominal pain, call your doctor immediately. There
is a higher risk of ectopic (outside the womb) pregnancy or ovarian
cysts with this type of contraceptive.
You should also be aware that OVRAL-L (Ovranette, Levlen, Levora, Nordette) have been know to
cause rare cases of noncancerous--but dangerous--liver tumors. In people
prone to high cholesterol and similar problems, OVRAL-L (Ovranette, Levlen, Levora, Nordette)
have been known to raise triglyceride levels, leading to pancreatitis.
If you use a combination oral contraceptive, be aware that it may
take a couple of months to get pregnant after you stop using it.
Possible food and drug interactions when taking OVRAL-L (Ovranette, Levlen, Levora, Nordette)
If OVRAL-L (Ovranette, Levlen, Levora, Nordette) are taken with certain other drugs, the effects
of either could be increased, decreased, or altered. It is especially
important to check with your doctor before combining OVRAL-L (Ovranette, Levlen, Levora, Nordette)
with the following:
Acetaminophen (Tylenol)
Amitriptyline (Elavil)
Ampicillin (Principen)
Aspirin
Atorvastatin (Lipitor)
Barbiturates (phenobarbital, Seconal)
Carbamazepine (Tegretol)
Chloramphenicol (Chloromycetin)
Clofibrate (Questran)
Clomipramine (Anafranil)
Cyclosporine (Neoral, Sandimmune)
Dexamethasone
Diazepam (Valium)
Doxepin (Sinequan)
Felbamate (Felbatol)
Fluconazole (Diflucan)
Glipizide (Glucotrol)
Griseofulvin (Fulvicin, Gris-PEG)
HIV protease inhibitor drugs such as Crixivan (indinavir)
Imipramine (Tofranil)
Itraconazole (Sporanox)
Ketoconazole (Nizoral)
Lorazepam (Ativan)
Metoprolol (Lopressor)
Modafinil (Provigil)
Morphine (MS Contin)
Oxazepam (Serax)
Oxcarbazepine (Trileptal)
Penicillin (Veetids, Pen-Vee K)
Phenylbutazone
Phenytoin (Dilantin)
Prednisolone (Prelone, Pediapred)
Prednisone (Deltasone)
Primidone (Mysoline)
Propranolol (Inderal)
Rifabutin (Mycobutin)
Rifampin (Rifadin, Rimactane)
St. John's wort
Sulfonamides (Bactrim, Septra)
Temazepam (Restoril)
Tetracycline (Sumycin)
Theophylline (Theo-Dur)
Topiramate (Topamax)
Troleandomycin (Tao)
Vitamin C
Warfarin (Coumadin)
In addition, before using the Yasmin brand of oral contraceptive check
with your doctor if you regularly take nonsteroidal anti-inflammatory
drugs such as Motrin and Aleve, potassium supplements such as Micro-K,
certain water pills such as Aldactone, and certain high blood pressure
medications, including Avapro, Capoten, Cozaar, Diovan, Vasotec, and
Zestril.
Remember, too, that OVRAL-L (Ovranette, Levlen, Levora, Nordette) may affect tests for blood
sugar levels and thyroid function and may cause an increase in blood
cholesterol levels.
Special information if you are pregnant or breastfeeding
If you are pregnant (or think you might be), you should not use OVRAL-L (Ovranette, Levlen, Levora, Nordette), since they are not safe during pregnancy. For safety's
sake, switch to a nonhormonal method of contraception if you miss a
period after forgetting a scheduled dose of the Pill. In addition,
wait at least 4 weeks after delivery before starting an oral contraceptive.
Nursing mothers should not use most OVRAL-L (Ovranette, Levlen, Levora, Nordette), since these
drugs can appear in breast milk and may cause jaundice and enlarged
breasts in nursing infants. In this situation, your doctor may advise
you to use a different form of contraception while you are nursing
your baby. However, progestin-only OVRAL-L (Ovranette, Levlen, Levora, Nordette) should not affect
your milk or your baby's health.
Recommended dosage for OVRAL-L (Ovranette, Levlen, Levora, Nordette)
If you have any questions about how you should take OVRAL-L (Ovranette, Levlen, Levora, Nordette),
consult your doctor or the patient instructions that come in the drug
package. The following is a partial list of instructions for taking
OVRAL-L (Ovranette, Levlen, Levora, Nordette); it should not be used as a substitute for consultation
with your doctor.
Some brands can be started on the first day of your menstrual cycle
or on the first Sunday afterwards. Others must be started on the fifth
day of the cycle or the first Sunday afterwards. The instructions below
are for the first-Sunday schedule.
OVRAL-L (Ovranette, Levlen, Levora, Nordette) are supplied in 21-day and 28-day packages.
FOR A 21-DAY SCHEDULE
Overdosage
While any medication taken in excess can cause overdose, the risk
associated with OVRAL-L (Ovranette, Levlen, Levora, Nordette) is minimal. Even young children
who have taken large amounts of OVRAL-L (Ovranette, Levlen, Levora, Nordette) have not experienced
serious adverse effects. However, if you suspect an overdose, seek
medical help immediately.
* Symptoms of overdose may include:
Drowsiness, fatigue, nausea, vomiting, withdrawal bleeding in females
