Brand name:
Antiosteoporotic Products
ALPHADOL (Alfacip, Alfacalcidol, One-Alpha. AlfaD)
Alfacalcidol Capsules
Composition
ALPHADOL (Alfacip, Alfacalcidol, One-Alpha. AlfaD) 0.25 micro gm
Each soft gelatin capsule contains alfacalcidol (1-alpha hydroxyvitamin
D 3 ) 0.25mcg (green capsule)
Description
Alfacalcidol (1-alpha hydroxy) undergoes rapid hepatic conversion
to 1,25 – dihydroxyvitamin D 3 the vitamin D 3 metabolite which
acts as a regulator of calcium and phosphate metabolism. The main effects
are to increase circulating 1, 25 dihydroxyvitamin D 3 levels,
and thereby to increase intestinal absorption of calcium and phosphate,
promote bone mineralisation, decrease plasma parathyroid hormone levels
as well as to decrease bone resorption, with relief of bone and muscle
pain. Treatment of intestinal calcium malabsorption associated with
post-menopausal, senile and steroid-induced osteoporosis, with ALPHADOL (Alfacip, Alfacalcidol, One-Alpha. AlfaD)
improves the negative calcium balance of these patients. The more positive
calcium balance produced by alfacalcidol treatment in the osteoporotic
patients, decreases bone loss and bone fracture rate.
Indications
ALPHADOL (Alfacip, Alfacalcidol, One-Alpha. AlfaD) is used for treating conditions in which calcium metabolism
is disturbed due to impaired 1-alpha hydroxylation, such as reduced
renal function; in other disorders associated with Vitamin D resistance;
and in calcium malabsorption of osteoporosis.
The main indications are:
•
Renal bone disease (renal osteodystrophy)
•
Hypoparathyroidism
•
Hypoparathyroidism (with bone disease)
•
Nutritional and malabsorptive rickets and osteomalacia
•
Hypophosphataemic Vitamin D-resistant rickets and osteomalacia
•
Pseudo-deficiency (D-dependent Type I) rickets with osteomalacia
•
Osteoporosis
Dosage And Administration ALPHADOL (Alfacip, Alfacalcidol,
One-Alpha. AlfaD) without prescriptions:
General
The dosage and administration of ALPHADOL (Alfacip, Alfacal